Precise and High-Sensitivity

The AccuMag Series by CELO

Magnetic Beads Separation Rack Capable of Single-cell Analysis

A New Standard for Single-Cell, Rare-Cell, and Micro-Volume Assays

AccuMag Series

Magnetic Separation Racks

CELO Biotech proudly presents the AccuMag Series — a revolutionary magnetic separation platform designed to push the detection limits of magnetic bead-based molecular assays. Whether you’re working with a few rare cells or aiming for scalable high-throughput screenings, AccuMag empowers your experiments with unmatched precision, efficiency, and reproducibility

The Common Problem of Conventional Magnetic Racks: Spread and Smeared Bead Patches After Separation, Causing Loss of Beads and Critical Signals After Recovery

Traditional standard magnetic racks often fail when processing low-volume or rare-cell samples. Magnetic beads tend to spread along the tube wall, making them difficult to retrieve — especially in sub-microvolume specimens. The samples may suffer from bead loss, low recovery rate, and leading to missing critical weak signals.

Beads Collected by Standard Magnetic Rack, Design Type 1

Beads Collected by Standard Magnetic Rack, Design Type 2

Beads Collected by Standard Magnetic Rack, Design Type 3

Example of bead separation on three standard design types of magnetic racks. Magnetic beads are spread and smeared on the tube wall, causing bead loss/signal drop between operations, particularly in small-volume specimens.

Breakthrough in Bead Enrichment: AccuMag vs. Standard Racks for Small-Volume Specimens

AccuMag’s patent pending magnetic core can concentrate beads into a tighter, sharp spot* smaller than a sesame seed. This eliminates beads spreading, boosts recovery, and improves detection precision — even down to single-cell scale. Simulation and field tests show AccuMag delivers better magnetic flux distribution at the target area of test tubes compared to traditional designs. *Specimens dependent

Test condition: 5 µl XP beads in 100 µl water. Incubated for 5 mins on magnetic rack indicated.

Beads Collected by AccuMag 4

Improved design. Condensed magnetic XP beads form a compact cluster in the test tube, making it easy to wash and retrieve. A sesame seed placed on the right for scale. 1.5 ml tube format.

Beads Collected by a Standard Magnetic Rack – Type 1

A common issue with standard magnetic racks is that the beads tend to spread & smeared into a thin layer on the surface of the test tube after collection. This condition leads to a significant loss of beads during operation, particularly with lower volume specimens. 1.5 ml tube format.

Beads Collected by a Standard Magnetic Rack – Type 2

Another type of standard magnetic rack structure commonly used in the market. The low amount of magnetic beads forms a stripe of thin layer spreading on the back of the test tube after collection. 1.5 ml tube format

Proven in Single-Cell Assays

In a pilot study using AccuMag 16, we successfully distinguished gene expression between single CHO-K1-GFP⁺ and CHO-K1-GFP⁻ cells using just 3 µl XP beads in PCR-strip format. The result? Clear cDNA profiles with no need for outsourcing or core-lab dependency such as scNGS assays

Beads Collected by AccuMag 16 / 96

Condensed magnetic XP beads form a compact cluster in the PCR tube, making it easy to wash and retrieve. 0.2 ml PCR tube

Single-cell transcription profile analysis using AccuMag 16

Single CHO-K1-GFP⁺ and control cells were subjected to RT assay. GFP transcription profile were detected in single CHO-K1-GFP⁺ groups

The AccuMag Series: Scalable Single-Cell Analysis

Achieve superior recovery yields in all your molecular cell biology magnetic bead assays for every stage

AccuMag 4

For 1.5 ml tubes, 4-sample processing
Ideal for samples up to 1500 µl.

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AccuMag 16

Supports 2× 8-well PCR strips
Optimal for low-volume assays in 0.2/0.1 ml tubes

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AccuMag 96

For 96-well PCR plates
Enables medium-scale automation-ready workflows

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AccuMag 384

For 384-well formats
Tailored for high-throughput screening platforms

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Custom platform fitting available for automated systems

Key Features

Ultra-High Recovery Yield

Optimizes bead retrieval by concentrating magnetic beads to a small area smaller than a sesame seed and significantly enhances the liquid handling experience in low-volume assays.

Micro-Volume Optimized

Enabling reliable single-cell and rare-cell analyses, offers more than ten times the sensitivity of conventional techniques.

Compatible with Standard Protocols

Works seamlessly with standard magnetic beads separation protocols—no specialized training required.

Economic Single-Cells Analysis

Perform rare-cell assays or single-cell transcriptome profiling without the requirement for costly external services or core-facility equipment required by conventional scNGS.

Stable and Reliable Results

The precisely engineered magnetic field ensures reliable, consistent bead collection, minimizing experimental variation.

Extend the detection limits

Why Choose AccuMag?

Do more in-house. AccuMag lets scientists do more in-house without core lab reliance. Save time, reduce cost, and increase discovery power.

Extend Assay Sensitivitye

Detect nucleic acids from <10 cells, even single-cell, using common protocols

Scalable Across Assay Sizes

From pilot tests to high-throughput screens, the AccuMag series share the same core technology. AccuMag 16 and AccuMag 96 have identical magnetic core in size

Rapid iterations

Reduces costs, delivers faster results, provides more experimental control, and eliminates dependence on the core lab

Plug-and-Play Workflow

No special reagents or training; compatible with standard lab tools

Sphroid or micorenvironment studies?

Synergize with DropletMatrix

For colony formation, organoid modeling, or suspension-based single-cell assays, AccuMag pairs perfectly with DropletMatrix, CELO’s suspension chip system. Together, they streamline the front-end of your precision medicine workflow.

Order AccuMag Today

Contact us for pricing, custom configurations, or trial kits.
📧 info@celobiotech.com
🔗 www.celobiotech.com/manual/am4 | YouTube Video Demo

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Partnering Opportunities

Let’s Create Together

CELO Biotech is actively seeking collaborations with research labs, CROs, and industry partners. If you’re working on cutting-edge biomedical R&D, let’s co-create the next breakthrough.

Reach out to us: info@celobiotech.com